Anne Froidebise studied at the Royal Conservatoires of Liège and Brussels, where she graduated in the three keyboard instruments: piano (class of Robert Leuridan), organ (class of Hubert Schoonbroodt) and harpsichord (class of Charles Koenig). She also received guidance from Xavier Darasse and Bernard Lagacé at summer academies.
Her interest in the entire organ repertoire has led her to perform on many instruments of differing aesthetics—old and modern, renowned and lesser-known.

In chamber music, she worked for around thirty years with flautists Jean-Paul and Emmanuel Pirard, with whom she gave very numerous concerts in Europe and the United States. As a harpsichordist, she took part in several complete concert cycles of works by Johann Sebastian Bach: flute sonatas, violin sonatas, and the first book of The Well-Tempered Clavier. She has appeared as a soloist with the Liège Philharmonic Orchestra and with various chamber orchestras.

Her discography is extensive, with more than twenty recordings.

Teaching represents a major part of her life as a musician. She was professor of organ at the Royal Conservatory of Liège from 1992 to 2015, and professor of harpsichord at IMEP from 1985 to 1996. Since 2011, she has taught in the summer at the International Academy of Music in Cornwall (AIMC).

Eager to promote wider knowledge of the organ and its music, she continues—within the association “Art et Orgue en Wallonie”—to raise public awareness by organising concerts, talks and guided tours, in collaboration with various partners.

A member of the Royal Commission for Monuments, Sites and Excavations of the Walloon Region from 1992 to 2014, she is currently vice-president of the Francophone Federation of Friends of the Organ (FFAO).